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Patients requiring blood almost never receive transfusions of whole blood.
Instead, a patient typically receives only the components necessary to
treat their clinical condition. Therefore, whole blood donations must
be processed to separate out each component. Each component plays a different
role in the health and survival of a patient.
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Red blood cells comprise
40-50% of blood volume. They carry oxygen to vital organs and are
required by surgical patients who lose blood during surgery or by
trauma victims who have lost blood as a result of an accident or injury.
Red blood cells that have been donated can be stored in a refrigerator
for up to 42 days. If they are not used within six weeks, they must
be thrown away. Red blood cells can also be stored frozen for up to
10 years. Red cells are the most commonly transfused blood component
and most whole blood collections are done with the specific intent
of capturing the red cell component. |
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| Red Blood Cells carry oxygen to organs. |
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Platelets account for
a small percentage of whole blood volume. They are used therapeutically
to control bleeding and are often transfused in multiple doses to
cancer patients undergoing chemotherapy. Platelets must be stored
at room temperature to retain their viability. Therefore, they have
only a five-day shelf life before they must be discarded due to possible
growth of bacteria. |
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| Platelets aid in clotting. |
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Plasma: The remainder of
blood volume is plasma, a watery substance in which proteins that
trigger blood-clotting mechanisms are suspended. Plasma can be transfused
directly to a patient, but, more often, plasma is used as a raw material
for pharmaceuticals. Plasma is “fractionated” into its different protein
components, which are then manufactured into pharmaceuticals. Factor
VIII, which is required by hemophiliacs to control bleeding, is one
such plasma-derived medicine. Plasma can be stored frozen for up to
one year. |
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| Plasma: the fluid portion of blood. |
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